Torque teno sus virus 1 and 2 viral loads in postweaning multisystemic wasting syndrome (PMWS) affected and non-affected pigs
Torque teno virus (TTV) is a small, non-enveloped virus with a circular single-stranded DNA genome, belonging to the family Anelloviridae, genus Iotatorquevirus and widely distributed in different animal species and humans. In swine, two genetically distinct genogroups have been identified, Torque teno sus virus 1 (TTV1) and 2 (TTV2). No clear-cut pathogenic role of TTVs has been demonstrated so far.
However, it has been shown that TTV2 prevalence is higher in postweaning multisystemic wasting syndrome (PMWS) affected pigs, and TTV1 has been linked to PMWS and a porcine dermatitis and nephropathy syndrome (PDNS)-like condition (1,2,3). Nevertheless, the TTV viral load in diseased animals has not been investigated. Therefore, the aim of the present study was to quantify TTV1 and TTV2 viral load in serum of PMWS-affected and healthy animals using a newly developed quantitative PCR (qPCR) method.
Mario Aramouni; Marina Sibila; Gerard E. Martin-Valls; David Nieto; Marti Cortey; Joaquim Segales; Tuija Kekarainen
CReSA/UAB, Bellaterra (Barcelona), Spain
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