Study: Reducing colonisation of Salmonella Typhimurium

30-09-2014 | | |
Study: Reducing colonisation of Salmonella Typhimurium

The aim of this study, presented recently in ASAS 2014, was to evaluate the effect of Gustor BP70 (partially protected sodium butyrate) for reducing gut colonization by Salmonella Typhimurium.

A total of 42 4-week-old commercial piglets were randomly distributed into two different experimental dietary groups (8 replicates per treatment).

Treatment 1 was a control diet without additives and treatment 2 was the same diet supplemented with 3 kg/t Gustor BP70. After 7 days of adaptation, the pigs were challenged with Salmonella Typhimurium (10 8 CFU). Faecal consistency and rectal temperature were evaluated 24 and 72 h post infection (PI). On day 1 and 7 PI, fecal secretion of Salmonella was evaluated. On day 4 and 8 PI, one animal per replicate was euthanized to evaluate inflammatory answer (TNF-α and Pig-Map plasmatics), histomorphological changes and Salmonella presence in colon (8 day PI).

There were no significant differences between treatments, in fecal consistency, rectal temperature or inflammatory indicators. There was a tendency (0.05

Source: Norel

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